Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis
نویسندگان
چکیده
منابع مشابه
Expression of Vascular Endothelial Growth Factor in Nasal Polyp and Chronic Rhinosinusitis
Background: Nasal inflammatory disorders such as chronic rhinosinusitis and nasal polyp are among the most prevalent complications with high socioeconomic costs. Vascular Endothelial Growth Factor (VEGF) plays a key role in angiogenesis and cell proliferation. In the present study the effect of VEGF on the development and prognosis of chronic rhinosinusitis and nasal p...
متن کاملComparison of Expression of Cytokeratin 7 on Epithelium of Nasal Polyps and Mucosa of Chronic Rhinosinusitis
Background and Objective: Nasal polyp is the most common benign mass of the nasal cavity and it is originated from nasal cavity or sinuses. Cytokeratins (CK) are intermediate filament proteins that provide mechanical support in epithelial cells. The purpose of this study was to compare the expression of cytokeratin 7 in epithelium of nasal polyps and nasal mucosa in chronic rhinosinusitis. Mate...
متن کاملTh17 Cytokines Disrupt the Airway Mucosal Barrier in Chronic Rhinosinusitis
Cytokine mediated changes in paracellular permeability contribute to a multitude of pathological conditions including chronic rhinosinusitis (CRS). The purpose of this study was to investigate the effect of interferons and of Th1, Th2, and Th17 cytokines on respiratory epithelium barrier function. Cytokines and interferons were applied to the basolateral side of air-liquid interface (ALI) cultu...
متن کاملLow SPINK5 expression in chronic rhinosinusitis.
OBJECTIVES/HYPOTHESIS Chronic rhinosinusitis (CRS) is a multifactorial disease that probably arises as a result of genetic diversity and environmental factors. SPINK5 is a serine protease inhibitor, which is supposed to be an important regulator of epithelial barrier maintenance. The role of SPINK5 polymorphisms and expression in CRS, especially in individuals with aspirin intolerance, is uncle...
متن کاملThe role of cytokines in rhinosinusitis.
Since the last decade, new insights into inflammatory processes have become possible by investigating the pattern of cytokines in acute and chronic sinus diseases. This review aims to update and discuss the findings of in vitro and in vivo studies concerning the role of cytokines in sinusitis and nasal polyposis. The proinflammatory cytokines interleukin-1beta, interleukin-6 and the neutrophil-...
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ژورنال
عنوان ژورنال: International Forum of Allergy & Rhinology
سال: 2012
ISSN: 2042-6976
DOI: 10.1002/alr.21133